LOUISVILLE, KY — An investigation is underway after a large UPS plane crashed near the Louisville, Kentucky, airport around 5:15 p.m. on Tuesday, according to the Louisville Metro Police Department.
LMPD and multiple agencies are responding to the reports of a plane crash near Fern Valley and Grade Lane.
Multiple injuries were reported, officials said.
UPS Airlines issued a brief statement saying, “UPS has been notified of an incident/accident involving one of our aircraft in Louisville, KY.”
The Federal Aviation Administration released a statement saying, “UPS Flight 2976 crashed around 5:15 p.m. local time on Tuesday, Nov. 4, after departing from Louisville Muhammad Ali International Airport in Kentucky. The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu. The FAA and NTSB will investigate. The NTSB will lead the investigation and will provide all updates. This information is preliminary and subject to change.”
Kentucky Gov. Andy Beshear released a statement saying: “Kentucky, we are aware of a reported plane crash near Louisville International Airport. First responders are onsite, and we will share more information as available. Please pray for the pilots, crew and everyone affected. We will share more soon.”
This is a developing story.
Rachel and I are praying for victims of the UPS plane that crashed during takeoff at 5:15 p.m. We have every emergency agency responding to the scene. There are multiple injuries and the fire is still burning. There are many road closures in the area – please avoid the scene.…
— Mayor Craig Greenberg (@LouisvilleMayor) November 4, 2025
Kentucky, we are aware of a reported plane crash near Louisville International Airport. First responders are onsite, and we will share more information as available. Please pray for the pilots, crew and everyone affected. We will share more soon.
— Governor Andy Beshear (@GovAndyBeshear) November 4, 2025
UPS Flight 2976 crashed around 5:15 p.m. local time on Tuesday, Nov. 4, after departing from Louisville Muhammad Ali International Airport in Kentucky. The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu. The FAA and NTSB will investigate.…
— The FAA ✈️ (@FAANews) November 4, 2025
LMPD and multiple other agencies are responding to reports of a plan crash near Fern Valley and Grade Lane. Grade lane will be closed indefinitely between Stooges and Crittenden. Injuries reported. pic.twitter.com/QB7YaWscat
— LMPD (@LMPD) November 4, 2025
UPS has been notified of an incident/accident involving one of our aircraft in Louisville, KY. Updates will be posted on https://t.co/zvvXSPZgid as they become available.
— UPS Airlines (@UPSAirlines) November 4, 2025
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